منابع مشابه
Bronchiolitis obliterans organising pneumonia associated with the use of nitrofurantoin.
The spectrum of nitrofurantoin lung injury continues to widen. The case histories are presented of two patients who developed lung disease associated with the use of nitrofurantoin with histological features of bronchiolitis obliterans organising pneumonia (BOOP), a rare but recognised form of drug induced injury. The two middle aged women presented with respiratory symptoms after prolonged tre...
متن کاملNitrofurantoin Cytotoxicity
A B S T R A C T Nitrofurantoin, a commonly used urinary tract antiseptic, has been associated with idiosyncratic pulmonary and hepatic damage. We have used human lymphocytes in vitro to explore the biochemical basis of susceptibility to nitrofurantoin toxicity. The drug itself did not damage the cells as assessed by trypan blue dye exclusion. In the presence of a mouse hepatic microsomal drug-a...
متن کاملFurazolidone and nitrofurantoin in the treatment of experimental Pneumocystis carinii pneumonia.
Furazolidone and nitrofurantoin, oral nitrofuran derivatives with broad-spectrum antimicrobial properties already in clinical use, were compared for activity against Pneumocystis carinii in an immunosuppressed rat model of P. carinii pneumonia. Furazolidone exhibited only slight activity as a prophylactic agent but was moderately effective in the therapy of pneumocystosis. The median histologic...
متن کاملExcretion studies of nitrofurantoin and nitrofurantoin with deglycyrrhizinated liquorice.
Nitrofurantoin and nitrofurantoin with liquorice were given to healthy volunteers and patients suffering from urinary tract infections. The excretion rates of the drug, colony counts and side effects were studied in patients and excretion rates in the volunteers. The excretion rates of the drug were significantly higher in patients receiving the drug with liquorice and also side effects were mi...
متن کاملRecurrent nitrofurantoin-induced giant cell interstitial pneumonia: Case report and literature review
Giant cell interstitial pneumonia (GIP) is a rare form of chronic interstitial pneumonia typically associated with hard metal exposure. Only two cases of GIP induced by nitrofurantoin have been reported in the medical literature. We are reporting a case of recurrent nitrofurantoin-induced GIP. Although extremely rare, GIP needs to be included in the differential diagnosis in patients with chron...
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ژورنال
عنوان ژورنال: American Journal of Roentgenology
سال: 1968
ISSN: 0361-803X,1546-3141
DOI: 10.2214/ajr.103.3.540